TissueGen® was established in 2000 by Dr. Kevin Nelson following his research with Dr. George Smith at UT Southwestern Medical Center at Dallas. Working in peripheral nerve regeneration, their research showed fascicle formation in regenerated nerves with the aid of fibers, convincing Dr. Nelson of the commercial viability of its fiber-based drug delivery technology.
The peripheral nerve regeneration work was the culmination of a long line of extremely successful experiments that demonstrated the benefit of drug delivery fibers in numerous applications. With Dr. Nadir Alikacem, for example, Dr. Nelson demonstrated the ability to load a small pharmaceutical agent onto a fiber to help stem the blindness that results from diabetes.
TissueGen has brought the scientific promise of implantable drug delivery via biodegradable fibers to commercial reality.